# promethazine

> English word · Noun · IPA /pɹə(ʊ)ˈmɛθ.ə.ziːn/ · frequency rank #94,146

## Definitions
1. A first-generation H₁ receptor antagonist derived from phenothiazine, used as antihistamine and antiemetic medication with strong sedative effects.

## Etymology
From pro(p)- + meth- + (phenothi)azine.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/promethazine