# point of departure

> English word · Noun

## Definitions
1. Synonym of starting point.
2. of abstract processes that can be compared to a voyage: initial circumstances. Frequent collocations include, but are not limited to
3. a dosage level at which additional administration of an agent significantly loses its efficacy

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/point-of-departure