# Lesch-Nyhan syndrome

> English word · Noun

## Definitions
1. A rare inherited genetic disorder, caused by a deficiency of HGPRT, in which uric acid builds up in all body fluids.

## Etymology
First clinically characterized by medical student Michael Lesch and his mentor, pediatrician William Nyhan, who published their findings in 1964.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/lesch-nyhan-syndrome