# estradiol

> English word · Noun · IPA /ˌɛs.tɹəˈdaɪˌɔl/ · frequency rank #40,236

## Definitions
1. A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C₁₈H₂₄O₂) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer.

## Etymology
Internationalism. From estratriene (“estra(triene)”) + diol. By surface analysis, estra- + di- + -ol.

## Common misspellings (13)
`esrtadiol`, `esstradiol`, `estardiol`, `estraddiol`, `estradilo`, `estradioll`, `estradoil`, `estraidol`, `estrdaiol`, `estrradiol`, `esttradiol`, `etsradiol`, `setradiol`

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/estradiol