# downtitrate

> English word · Verb

## Definitions
1. To gradually reduce a dosage while observing the effects; (and usually, especially) to arrive at the optimal dose by so doing.

## Etymology
From down- + titrate; compare also upregulate and downregulate.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/word/downtitrate