# serene vs serine

> English confusable word pair

## The two words

### serene
*adjective · IPA /səˈɹi(ː)n/ · frequency rank #20,490*
Calm, peaceful, unruffled.

### serine
*noun · frequency rank #45,078*
A nonessential amino acid, CH₂OH.CH(NH₂)COOH, found in most animal proteins, notably silk.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/vs/serene-vs-serine