# serena vs serine

> English confusable word pair

## The two words

### serena
*noun · frequency rank #12,323*
Obsolete form of serene (“fine rain from a cloudless sky after sunset”, noun).

### serine
*noun · frequency rank #45,078*
A nonessential amino acid, CH₂OH.CH(NH₂)COOH, found in most animal proteins, notably silk.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/vs/serena-vs-serine