nucleivsnucleicWhich spelling fits?

Quick tell: nuclei is a noun, nucleic is an adjective, so they fill different roles in a sentence.

Which to use

“nuclei” is a noun and “nucleic” is an adjective - they look or sound alike but fill different roles in a sentence.

#22,751
“nuclei” frequency rank
#32,517
“nucleic” frequency rank
55268
confusion score

Side-by-Side Comparison

Feature nuclei nucleic
Definition plural of nucleus Referring to the nucleus of something.

Letter map: nuclei vs nucleic

Shared letters muted; letters that set nuclei and nucleic apart highlighted. Shared run: 6. nuclei runs 6 letters (CVCCVV) against nucleic's 7 (CVCCVVC) - the length gap alone is often enough to separate them once you know to check it.

6 ch
nuclei
7 ch
nucleic

Part-of-speech tell for nuclei / nucleic

Our dataset has no pronunciation recorded for both members, so the reliable separator here is grammatical: nuclei is anoun and nucleicanadjective. On the page they differ by 1 extra letter(s) - “nuclei” sits inside “nucleic”. Our composite confusion score for this pair is 55268, derived from the frequency rank of both members and their visual similarity.

nuclei is recorded at frequency rank #22,751, classified as anoun, pronounced /ˈnjuː.kli.aɪ/. nucleic is at rank #32,517, tagged as anadj.

Glosses for this pair are partially populated in our dataset, but the full side-by-side definitions above should still guide you to the right choice.

With a confusion score of 55268, this pair ranks #134,903 of 530,003 scored English confusable pairs - among the most confusable pairs.

Orthographic DNA of nuclei vs nucleic

Shared letters: ceilnu. Private to "nuclei": -. Private to "nucleic": -.

"nuclei" · 6 letters · shape CVCCVV  ·  "nucleic" · 7 letters · shape CVCCVVC

Known mistypes of this pair

  • nuclei ← nculei · nnuclei · nucclei · nuceli · nuclie · nucllei · nulcei · unclei
  • nucleic ← nculeic · nnucleic · nuccleic · nucelic · nucleci · nucleicc · nucliec · nuclleic

Frequently Asked Questions

Is swapping "nuclei" for "nucleic" ever safe?
No - they are not even the same part of speech. "nuclei" is a noun and "nucleic" an adjective, so a sentence built for one is usually ungrammatical with the other.
In ordinary English text, does "nuclei" or "nucleic" show up more?
"nuclei" is the more common of the two: it sits at frequency rank #22,751 in our English list, against #32,517 for "nucleic". The two are close in frequency, so neither is a safe default; check the meaning rather than guessing.

Useful next steps

Done with this confusable. These links stay specific to "nuclei" and "nucleic".

  • Full dictionary entry for "nuclei" with definition, IPA, and generated misspellings. Word entry
  • Full dictionary entry for "nucleic" - compare definitions side by side with the headword page. Word entry
  • This pair ranks #134,903 of 530,003 scored English confusable pairs in this corpus vintage. Corpus statistics
  • "nuclei" and "nucleic" also get mixed up with nearby pairs, the highest-scored neighbour is "nucleic vs nucleus". Nearby pair
  • Recorded mistypes exist for at least one side of this pair, useful when a spell-checker or OCR lands on the wrong form. See mistypes

Confusion rank #134,903 of 530,003 scored English pairs, corpus vintage 2026-09-03, not spelling advice.

Source: Wiktionary (via kaikki.org) Structured Wiktionary extract

Source: FrequencyWords open word-frequency list