# locus vs lupus

> English confusable word pair

## The two words

### locus
*noun · IPA /ˈləʊkəs/ · frequency rank #23,026*
A place or locality, especially a centre of activity or the scene of a crime.

### lupus
*noun · IPA /ˈluːpəs/ · frequency rank #22,427*
Any of a number of autoimmune diseases, the most common of which is systemic lupus erythematosus.

## Source
Compiled from Wiktionary via kaikki.org (CC BY-SA). Data vintage: 2026-05-06.
Canonical page: https://plainspell.com/en/vs/locus-vs-lupus